EU research into alternatives to animal testing - Joint diXa-ESNATS Training Course

Date: 27th – 28th August 2013
Venue: University of Cologne (UKK), Cologne, Germany
*This course has been cancelled*

This course is jointly organised by the diXa project and the ESNATS project.

The ESNATS - Embryonic Stem cell-based Novel Alternative Testing Strategies – Project aims to develop a novel toxicity test platform based on embryonic stem cells (ESCs), in particular human ESC (hESCs) to accelerate drug development, reduce related R&D costs and propose a powerful alternative to animal tests. The Data Infrastructure for Chemical Safety (diXa) project works with past and current EU FP7 projects, developing Alternatives to Animal testing, to safeguard data for the future. diXa aims to develop a sustainable data infrastructure to capture all data produced by toxicogenomics projects in a standardized, harmonized and sustainable manner. The lack of such an infrastructure currently prevents innovative breakthroughs from meta-analyses of joint databases and systems modeling. The diXa Data Warehouse will link to other globally available chemical/toxicological databases and data bases on molecular data of human disease to facilitate interdisciplinary research.

The ESNATS project finishes at the end of September 2013 and they will be presenting their results during this joint training course. The aim is for ESNATS data to be freely available through the diXa data warehouse.

The course will be a combination of presentation and hands-on data sessions and is aimed at PhD students, postdocs and researchers from academia as well as industry. A poster session is included during lunch time on day 2, one of the submitted abstracts will be chosen to give a short presentation during day 1.

Draft programme - subject to change

Time Topic  Speaker
Day 1: 27th August 2013
13:00 - 13:30  Registration
13:30 - 13:40  Welcome
13:40 - 14:10  Introduction to the diXa project Jos Kleinjans
14:10 - 14:40  CarcinoGENOMICS Jos Kleinjans
14:40 - 15:00  Short talk chosen from poster abstracts (15 min + questions) TBC
15:00 - 15:30  Break
15:30 - 16:15 Developmental Toxicity Testing with Human Pluripotent Stem Cell in ESNATS; Transcriptome level assessment Antony Gaspar
16:15 - 17:00  Data collected in ESNATS related to liver and stem cell work Joery de Kock
19:00  Conference Dinner & Drinks
Day 2: 28th August 2013
09:30 - 10:15 Purpose of the ESNATS consortium Tanja Waldmann (UKN)
10:15 - 11:00 Primary hepatocytes and embryonic stem cell derived hepatocyte like cells: possibilities and limitations Prof. Jan G. Hengstler (IfADo)
11:00 - 11:30 Break
11:30 - 12:15 Human embryonic stem cells in developmental neurotoxicity testing Prof. Jan G. Hengstler (IfADo)
12:15 - 13:30 Lunch - posters session
13:30 - 14:15 DETECTIVE at diXa Dr. Dimitry Spitkovsky
14:15 - 15:00 The diXa data warehouse Ekaterina Pilicheva
15:00 - 15:30 Break
15:30 - 17:00 How “we” integrate all the data from ESNATS? Raivo Kolde

End of Day 2

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